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Dyslipidemia and its Association with Meibomian Gland Dysfunction: A Systematic Review
Robin K Kuriakose1, Puneet S Braich2
1Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
International Ophthalmology
|July 9, 2017
Summary
Meibomian gland dysfunction (MGD) is strongly linked to dyslipidemia, a condition affecting blood lipid levels. Eye care practitioners may identify patients with dyslipidemia through MGD detection, aiding cardiovascular disease risk assessment.
Area of Science:
- Ophthalmology
- Cardiology
- Metabolic Disorders
Background:
- Meibomian gland dysfunction (MGD) affects the oil glands in the eyelids.
- Dyslipidemia involves abnormal levels of lipids in the blood, a risk factor for cardiovascular disease.
Purpose of the Study:
- To systematically review the literature on the association between MGD and dyslipidemia.
- To explore the potential role of eye care practitioners in identifying dyslipidemia.
Main Methods:
- A systematic literature search was conducted using the Medline database.
- Four relevant studies were identified and reviewed.
Main Results:
- Three out of four studies found a significantly higher prevalence of dyslipidemia in individuals with MGD.
- Age, total cholesterol, LDL, HDL, and triglycerides showed significant associations with MGD.
- Specific MGD subsets, like males aged 24-64, exhibited higher total cholesterol levels.
Conclusions:
- A strong positive correlation exists between MGD and dyslipidemia, though causality is not established.
- MGD detection by eye care practitioners may identify undiagnosed dyslipidemia.
- Further research could explore combined management strategies for MGD and dyslipidemia.

