Related Experiment Video
Updated: Feb 27, 2026
Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Evaluation of white matter hypodensities on computed tomography in stroke patients using the Fazekas score
Salvatore Rudilosso1, Luis San Román2, Jordi Blasco2
1Functional Unit of Cerebrovascular Diseases, Hospital Clinic, Barcelona, Spain.
Purpose:
To assess the reliability of the Fazekas score on brain CT in acute stroke patients.
Methods:
Two raters evaluated the Fazekas score in 157 CT scans from consecutive patients with acute stroke.
Results:
The Fazekas scores on brain CT scans showed consistent (weighted κ, 0.73) and moderate (weighted κ, 0.56) interobserver agreement for periventricular and deep white matter areas, respectively. Intraobserver reliability was substantial for both areas (weighted κ, 0.85 and 0.8).
Conclusion:
The Fazekas score on CT can be used to reliably grade white matter changes, and can be a useful tool when MRI is not available.
