Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.7K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.4K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.2K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

2.0K
Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Energy-Based Phase-Locking State Analysis in Brain State Identification.

Human brain mapping·2026
Same author

Neuromodulation-induced normalization of cortical metastable dynamics signatures in Parkinson's disease.

NPJ Parkinson's disease·2026
Same author

De novo genome assembly and annotation of Gnathostoma spinigerum.

Parasites & vectors·2026
Same author

An Unusual Presentation of Human Parotid Filariasis.

Tropical medicine and infectious disease·2025
Same author

Network pharmacology combined with experiments to explore the molecular mechanism of Jiawei Erzhi pill protects against atherosclerosis by inhibiting ferroptosis.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan·2025
Same author

Silicate chemical weathering disrupts the global patterns of phosphorus limitation.

Nature communications·2025
Same journal

Validating a point-of-care test for Toxoplasma gondii infection in southern sea otters (Enhydra lutris nereis).

Parasitology research·2026
Same journal

Vector-borne pathogen evaluation and phylogenetic analysis in working K9 dogs in Iraq: implications for canine and public health.

Parasitology research·2026
Same journal

Two key Actinomycetota taxa in the human gut microbiota are associated with Schistosoma mansoni infection burden.

Parasitology research·2026
Same journal

Gastrointestinal parasites circulating in wild boars from central Italy and molecular characterization of Balantioides coli, Blastocystis sp. and Enterocytozoon bieneusi.

Parasitology research·2026
Same journal

G6PD deficiency and the exportome of plasmodium falciparum FCB-2: a comparative analysis utilizing one-dimensional blue-native electrophoresis and timstof mass spectrometry.

Parasitology research·2026
Same journal

First record of the parasite fauna of Serrasalmus geryi Jegú & Santos, 1988 (Characiformes: Serrasalmidae) and ecological implications of its invasion in a Neotropical floodplain.

Parasitology research·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products
12:40

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

Published on: April 6, 2015

19.5K

Parasites and asthma.

Lin Wuhao1,2, Chen Ran1,2, He Xujin3

  • 1Zhongshan School of Medicine, Sun Yat-sen University, 74 2nd Zhongshan Road, Guangzhou, 510080, China.

Parasitology Research
|July 10, 2017
PubMed
Summary
This summary is machine-generated.

Parasitic infections may prevent asthma by modulating immune responses. This review explores how helminth infections and immune cells like regulatory T cells offer protection against allergic airway inflammation, paving the way for new asthma therapies.

Keywords:
AsthmaParasitePreventionTherapy

More Related Videos

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
09:58

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Published on: June 5, 2012

14.3K
Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
15:01

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

3.8K

Related Experiment Videos

Last Updated: Feb 27, 2026

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products
12:40

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products

Published on: April 6, 2015

19.5K
Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
09:58

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Published on: June 5, 2012

14.3K
Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
15:01

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

3.8K

Area of Science:

  • Immunology
  • Parasitology
  • Allergy and Asthma Research

Background:

  • The hygiene hypothesis suggests a link between reduced parasitic infections and increased asthma prevalence.
  • Observational studies indicate lower asthma morbidity in areas endemic for parasitic diseases.

Purpose of the Study:

  • To review the relationship between parasitic infections and asthma.
  • To elucidate the protective mechanisms of parasites against asthma.
  • To explore potential therapeutic strategies for asthma based on parasitic interactions.

Main Methods:

  • Literature review of studies investigating the impact of parasitic infections on asthma.
  • Analysis of immune response modulation (Th1/Th2 shift) induced by parasites.
  • Identification of key immune cells and cytokines involved in parasite-mediated asthma protection.

Main Results:

  • Parasitic infections can induce a shift from Th1 to Th2 immune responses, potentially suppressing allergic inflammation.
  • Specific immune cells, including regulatory T cells, regulatory B cells, dendritic cells, and alternatively activated macrophages, are implicated.
  • Cytokine Interleukin-10 (IL-10) plays a crucial role in protecting against allergic airway inflammation.

Conclusions:

  • Parasitic infections offer a protective effect against asthma development and allergic airway inflammation.
  • Understanding parasite-induced immune modulation provides insights into novel therapeutic targets for asthma.
  • Further research into helminth-derived immunomodulation could lead to innovative asthma treatments.