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Autoamputation and Polyneuropathy in Mixed Connective Tissue Disorder: A Case Report
Syeda Naqvi1, Vikash Talib2, Razia Aijaz3
1Jinnah Postgraduate Medical Centre, Jinnah Sindh Medical University (SMC).
Cureus
|July 11, 2017
Summary
Mixed connective tissue disorder (MCTD) is a rare autoimmune condition. This case study highlights the extremely rare co-occurrence of polyneuropathy and autoamputation in a young woman with MCTD.
Area of Science:
- Rheumatology
- Immunology
- Neurology
Background:
- Mixed connective tissue disorder (MCTD) is a rare multisystem autoimmune disease.
- It exhibits overlapping features of systemic lupus erythematosus (SLE), myositis, rheumatoid arthritis, and scleroderma.
- A hallmark of MCTD is the presence of U1-ribonucleoprotein (RNP) antibodies in serum.
Keywords:
autoamputationcalcinosismixed connective tissue disorderpolyneuropathyraynaudssclerodactylysensorimotor neuropathy
