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Prognostic value of brachial-ankle pulse wave velocity in patients with non-ST-elevation myocardial infarction

Hyun Woong Park1, Min Gyu Kang, Kyehwan Kim

  • 1aDivision of Cardiology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Jinju bDivision of Cardiology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea.

Coronary Artery Disease
|July 11, 2017
PubMed

Insights

Brachial-ankle pulse wave velocity (baPWV) is a valuable tool for predicting major adverse cardiovascular events (MACE) in non-ST-elevation myocardial infarction (NSTEMI) patients. Higher baPWV indicates increased risk, aiding clinical prognosis.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Clinical Research

Background:

  • Brachial-ankle pulse wave velocity (baPWV) is established for assessing arterial stiffness and cardiovascular risk.
  • The prognostic utility of baPWV in non-ST-elevation myocardial infarction (NSTEMI) patients remains unclear.

Purpose of the Study:

  • To evaluate the prognostic value of baPWV in patients diagnosed with NSTEMI.
  • To determine if baPWV can predict major adverse cardiovascular events (MACE) in this patient cohort.

Main Methods:

  • A cohort of 411 NSTEMI patients who underwent percutaneous coronary intervention and baPWV measurement was studied.
  • Outcomes including cardiac mortality and MACE (cardiac death, re-MI, revascularization, heart failure, stroke) were analyzed over a mean follow-up of 350 days.

Main Results:

  • MACE occurred in 6.3% and cardiac mortality in 3.1% of patients.
  • High baPWV levels were significantly associated with increased MACE and cardiac mortality.
  • Multivariable analysis identified high baPWV as an independent predictor of MACE (HR: 2.55, P=0.043).

Conclusions:

  • baPWV is a strong, independent prognostic factor for MACE in NSTEMI patients.
  • baPWV offers a simple, less invasive method for predicting MACE in NSTEMI patients in clinical practice.
Abstract

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