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The Use of Branched Endografts for the Aortic Arch in the Endovascular Era
Rami O Tadros1, Scott R Safir2, Peter L Faries3
1Department of Surgery and Radiology, Vascular Surgery Residency Off-site Vascular Lab, Division of Vascular Surgery, Icahn School of Medicine at Mount Sinai Hospital, New York, New York.
Insights
Endovascular aortic arch repair offers a less invasive alternative to open surgery for patients with comorbidities. Continued development of branched endografts aims to improve outcomes and reduce stroke risk.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Medical Device Engineering
Background:
- Endovascular techniques are increasingly used for aortic disease, but the aortic arch remains challenging.
- Open surgery for aortic arch pathology is associated with high morbidity and mortality, especially in patients with comorbidities or prior cardiac surgery.
- The development of advanced endovascular systems and custom-made grafts is crucial for treating complex aortic arch anatomies.
Purpose of the Study:
- To review the current status and challenges of endovascular treatment for aortic arch pathology.
- To discuss the technical aspects of branched endograft deployment in the aortic arch.
- To highlight the potential benefits and risks of endovascular aortic arch repair.
Main Methods:
- Review of existing literature and endovascular device advancements for aortic arch repair.
- Description of typical procedural steps, including stent-graft deployment and bridging techniques.
- Discussion of anatomical considerations and the use of custom-made or modified devices.
Main Results:
- Branched endografts aim to exclude aneurysms while preserving flow to supra-aortic vessels.
- Technical success and device durability are influenced by the aortic arch's complex anatomy.
- Potential complications include stroke and paraplegia due to catheter and wire manipulation.
Conclusions:
- Endovascular-only techniques for aortic arch pathology are becoming more important due to an aging population and increased comorbidities.
- Further experience and technological advancements are needed to improve patient outcomes and device durability.
- Endovascular repair presents a viable alternative for patients who are poor candidates for open surgery.
Abstract:
The endovascular realm has steadily increased its footing in the treatment of the aorta and all of its territories since the foundational case in 1990 by Parodi. The aortic arch, however, continues to be one of the last bastions for treatment via open surgery, which remains the gold standard. Significant comorbidity and prior cardiac surgery prevent open surgery from being the only preferred option, allowing novel endovascular procedures to be considered. Since 1999, more advanced endovascular systems have been created by companies such as Cook Medical, Bolton Medical, Medtronic, Endospan, Gore Medical, and, recently, Kawasumi. The unique shape and angulation of the aortic arch often require the use of custom-made grafts, though arch reconstruction may also include in situ or back-table physician alterations to off-the-shelf devices. The goal of branched endografts is to exclude the aneurysm, while maintaining flow to supra-aortic trunk vessels. Technical success and device durability are limited by the physical constraints of the aortic arch, though greater experience may yield better patient outcomes. Typically, the initial stent-graft (SG) is introduced and deployed into the arch first. Bridging SG are then inserted via axillary or carotid access. Most often, the bridging SG extends from the innominate branch to the distal innominate, and from the left carotid branch to the left common carotid. The major concern is that manipulation of catheters and wires, both within the carotid arteries and aortic arch, create the potential for emboli leading to stroke and paraplegia. The development of endovascular-only techniques for aortic arch pathology will only increase with the aging population of the United States and associated accumulation of comorbidities, making open surgery too grave of a risk.
