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Dermatofibrosarcoma protuberans of the breast: A case report
Kamil Pohlodek1, Iveta Mečiarová2, Petr Grossmann3,4
1The Second Department of Gynecology and Obstetrics, Faculty of Medicine, Comenius University of Bratislava, 82606 Bratislava, Slovakia.
Oncology Letters
|July 12, 2017
Summary
Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing subcutaneous tumor. This case report details a breast cancer diagnosis and treatment of DFSP in a 43-year-old woman.
Area of Science:
- Oncology
- Genetics
- Dermatology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare malignant neoplasm of the skin and subcutaneous tissue.
- DFSP exhibits slow, infiltrative growth and can occur across various age groups, with peak incidence between the second and fifth decades.
- Genetic hallmarks include t(17;22) translocation or ring chromosomes involving chromosomes 17 and 22.
Purpose of the Study:
- To present a case report of Dermatofibrosarcoma protuberans (DFSP) in the breast.
- To discuss the clinical presentation, diagnosis, and treatment of this rare tumor.
- To evaluate the characteristics and management options for DFSP.
Main Methods:
- Case report of a 43-year-old female patient with a breast tumor.
- Surgical excision with breast-conserving surgery.
- Histological and cytogenetic examination for tumor diagnosis.
Main Results:
- Diagnosis of Dermatofibrosarcoma protuberans (DFSP) confirmed through histological and cytogenetic analysis.
- The patient underwent successful breast-conserving surgery.
- Clinical and morphological features of the DFSP were evaluated.
Conclusions:
- Dermatofibrosarcoma protuberans (DFSP) can manifest in the breast, requiring accurate diagnosis and appropriate surgical management.
- Breast-conserving surgery is a viable treatment option for localized DFSP.
- Further evaluation of DFSP characteristics and treatment strategies is essential.
