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Published on: June 13, 2021
Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
Yue-Zhi Dong1, Fei-Jing Zhou1, Ying-Pu Sun2
1Reproductive Medicine Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshedong Road, Erqi District, Zhengzhou, Henan Province, 450052, China.
Background:
Stress exposure has been proved to be linked to reproductive failure. The reproductive potential of women depends on the ovarian reserve. Anti-müllerian hormone (AMH) has been proved a reliable clinical marker of ovarian reserve. However, the correlation between psychological stress and AMH level is not clear.
Methods:
A cross-sectional study including 576 women was conducted. AMH concentration was tested to reflect the ovarian reserve. Salivary alpha-amylase (SAA) level was measured to assess the stress of patients objectively.
Results:
The SAA level was significantly, and negatively correlated with AMH levels in infertile women (r = -0.315, P = 0.000; adjusted for age, r = -0.336, P = 0.000).
Conclusion:
Higher psychological stress was related to a decreased AMH level in infertile women and psychological stress may affect ovarian reserve.
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