Related Experiment Video
Updated: Feb 26, 2026

05:44
Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
Published on: May 17, 2024
1.2K
Type 1 neurofibromatosis complicated by pulmonary arterial hypertension: A case report
Murathan Küçük, Can Ramazan Öncel1, Mustafa Uçar
1Department of Cardiology, Bucak State Hospital, Burdur, Turkey. r_oncel@hotmail.com.
Abstract:
Neurofibromatosis type I (NF1) is a rare genetic disease caused by mutations in the NF1 gene, which encodes the tumor suppressor neurofibromin. Precapillary pulmonary hypertension is a severe complication of NF1, initially described in patients with advanced parenchymal lung disease, which may complicate the course of NF1. Presently described is a case of neurofibromatosis complicated by pulmonary hypertension.

