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Ophthalmic Artery Chemosurgery: A Nursing Perspective
Mary Elizabeth Davis1, Edith Guarini1, Lindsey Eibeler1
1Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Insights
Ophthalmic artery chemosurgery (OAC) offers a highly effective treatment for retinoblastoma (RB), achieving over 98% survival. This focused chemotherapy delivery minimizes systemic toxicity, improving outcomes for children with eye cancer.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Interventional Radiology
Background:
- Retinoblastoma (RB) is the most common pediatric eye cancer, with significant global mortality.
- Current treatments have limitations, and a need exists for more effective, less toxic therapies.
Purpose of the Study:
- To highlight the efficacy of ophthalmic artery chemosurgery (OAC) as a first-line treatment for RB.
- To emphasize the critical role of a multidisciplinary team, particularly nursing, in managing RB patients undergoing OAC.
Main Methods:
- Ophthalmic artery chemosurgery (OAC) involves direct delivery of concentrated chemotherapy to the ocular tumor.
- This study focuses on the team approach, nursing navigation, and patient/family education in the OAC treatment pathway.
Main Results:
- OAC has resulted in a survival rate exceeding 98% in over 1500 procedures performed.
- This approach delivers chemotherapy directly to the tumor, avoiding systemic toxicities.
Conclusions:
- OAC is a highly successful and standard first-line therapy for retinoblastoma.
- A multidisciplinary team approach, with integral nursing support and clear communication, is crucial for successful RB management and patient outcomes.
Abstract:
Retinoblastoma (RB) is the most common primary cancer to affect the eyes in children with approximately 350 cases/year in the United States and 8000 worldwide. Today, sadly, 50% of children with RB worldwide die from their disease. In our experience, utilization of ophthalmic artery chemosurgery (OAC) has transformed the treatment plan for patients; with over 1500 procedures performed, our survival rate exceeds 98%. It is now our standard first-line therapy for RB. OAC is a surgical outpatient procedure which delivers concentrated doses of chemotherapy directly to the tumor without the toxicities of systemic chemotherapy. Our team approach and nursing management of these patients are the focus of this article. Nursing navigation and collaboration after OAC is vital and requires a combined effort by the nurses along with physicians, interventional radiologists, and the patient's families to ensure appropriate follow-up is established. Proper patient education throughout the process is crucial as is open and available communication for parents of patients with the nursing staff. The success in our treatment of this disease can be much accredited to the multidisciplinary team approach, with nursing playing an integral part in the support and management of these patients.
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