Related Experiment Video
Updated: Feb 26, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
Ophthalmic Artery Chemosurgery: A Nursing Perspective
Mary Elizabeth Davis1, Edith Guarini1, Lindsey Eibeler1
1Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ophthalmic artery chemosurgery (OAC) offers a highly effective treatment for retinoblastoma (RB), achieving over 98% survival. This focused chemotherapy delivery minimizes systemic toxicity, improving outcomes for children with eye cancer.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Interventional Radiology
Background:
- Retinoblastoma (RB) is the most common pediatric eye cancer, with significant global mortality.
- Current treatments have limitations, and a need exists for more effective, less toxic therapies.
Purpose of the Study:
- To highlight the efficacy of ophthalmic artery chemosurgery (OAC) as a first-line treatment for RB.
- To emphasize the critical role of a multidisciplinary team, particularly nursing, in managing RB patients undergoing OAC.
Main Methods:
- Ophthalmic artery chemosurgery (OAC) involves direct delivery of concentrated chemotherapy to the ocular tumor.
- This study focuses on the team approach, nursing navigation, and patient/family education in the OAC treatment pathway.
Main Results:
- OAC has resulted in a survival rate exceeding 98% in over 1500 procedures performed.
- This approach delivers chemotherapy directly to the tumor, avoiding systemic toxicities.
Conclusions:
- OAC is a highly successful and standard first-line therapy for retinoblastoma.
- A multidisciplinary team approach, with integral nursing support and clear communication, is crucial for successful RB management and patient outcomes.
More Related Videos
10:10Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
13:12Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
Published on: October 15, 2017
Related Concept Videos
Angle Closure Glaucoma: Treatment
Peripheral Artery Disease V: Postoperative Nursing Management
Aneurysm IV: Nursing Management
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Cardiac Catheterization IV: Nursing Management