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Living with the Effects of Cutaneous Toxicities Induced by Treatment

Andreas Charalambous1,2

  • 1Department of Nursing, Cyprus University of Technology, Limassol, Cyprus, Finland.

Asia-Pacific Journal of Oncology Nursing
|July 12, 2017
PubMed

Insights

Targeted cancer therapies cause skin side effects, impacting patients' physical, social, and psychological well-being. Understanding the patient experience is crucial for improving care and quality of life during treatment.

Area of Science:

  • Oncology
  • Dermatology
  • Pharmacology

Background:

  • Targeted therapies offer significant cancer treatment benefits, including improved survival.
  • These therapies frequently cause systemic side effects, notably various cutaneous toxicities.
  • Specific drug classes implicated include EGFR, VEGF, KIT, PDGFR, BCR-ABL, and mTOR inhibitors.

Purpose of the Study:

  • To investigate the impact of targeted therapy-induced cutaneous toxicities on patients' quality of life.
  • To explore the physical, social, and psychological aspects of living with these side effects.
  • To highlight the need for understanding the patient perspective in managing treatment toxicities.

Main Methods:

  • Literature review on targeted therapies and their dermatological side effects.
  • Analysis of existing studies on patient-reported outcomes and quality of life.
  • Identification of research gaps concerning patient experiences with treatment toxicities.

Main Results:

  • Cutaneous toxicities are common side effects of numerous targeted cancer therapies.
  • Limited research exists on the comprehensive impact of these toxicities on patients' daily lives.
  • The physical, social, and psychological burden on patients is not well-documented.

Conclusions:

  • Targeted therapies, while effective, present significant dermatological challenges.
  • Further research is essential to understand and address the patient experience of these toxicities.
  • Incorporating patient perspectives is key to optimizing supportive care and improving quality of life for cancer patients.
Keywords:
Cutaneous toxicitiesquality of lifetargeted therapies

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