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Prenatal management of fetal intrapericardial teratoma: a systematic review

Ahmed A Nassr1,2, Sherif A Shazly3, Shaine A Morris4

  • 1Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Fetal Center, Houston, TX, USA.

Prenatal Diagnosis
|July 12, 2017
PubMed

Insights

This systematic review examines prenatal management for fetal pericardial teratoma. Prenatal interventions show potential benefits, but outcomes require careful consideration due to associated risks.

Area of Science:

  • Perinatology
  • Fetal Medicine
  • Pediatric Surgery

Background:

  • Fetal pericardial teratoma is a rare congenital tumor.
  • Management strategies and outcomes require further elucidation.

Purpose of the Study:

  • To comprehensively review the clinical course, perinatal outcomes, and effectiveness of prenatal management for fetal pericardial teratoma.

Main Methods:

  • Systematic literature search of Ovid MEDLINE, EMBASE, and Scopus up to September 2016.
  • Inclusion of studies reporting prenatal course of pericardial teratoma in singleton or twin gestations.
  • Data abstraction by two independent reviewers using standardized forms.

Main Results:

  • 67 fetuses with pericardial teratoma were identified across 59 studies.
  • Prenatal intervention was performed in 26 fetuses, with 75% favorable outcomes in those who were hydropic.
  • In the non-intervention group, 30.8% of hydropic fetuses had a favorable outcome.

Conclusions:

  • Prenatal interventions like fluid drainage have been used for intrapericardial teratoma.
  • Neonatal benefit of pericardiocentesis is uncertain; other interventions show variable success.
  • Prenatal intervention may be considered in specialized centers, balancing maternal and fetal risks.
Abstract

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