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Abstract:
The normal microscopic and gross morphologic features of the stomach are described. Emphasis is given to mucosal anatomy and the recognition of minor alterations seen in disease that may be identified on an endoscopic biopsy. Advice is given in the interpretation of biopsy artefact that may present diagnostic problems. The various types of gastric metaplasia are discussed both in relation to altered morphology and to changes in mucin histochemistry.