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The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
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An innovative method for precise lymph node detection before surgical treatment in breast cancer
Milovan Matovic1, Dalibor Nikolic, Nenad Filipovic
1University of Kragujevac, Faculty of Medical Sciences, Bioengineering Research and Development Center, Kragujevac, Serbia. mmatovic1955@gmail.com.
Hellenic Journal of Nuclear Medicine
|July 12, 2017
Summary
This study introduces a new 3D modeling technique integrating SPECT and MSCT imaging for precise sentinel lymph node (SNL) localization in breast cancer (BC) patients, offering a faster and more accurate alternative.
Area of Science:
- Medical Imaging
- Oncology
- Surgical Navigation
Background:
- Accurate sentinel lymph node (SNL) localization is crucial for staging breast cancer (BC).
- Traditional methods for SNL identification can be time-consuming and less precise.
Observation:
- A novel 3D interactive modeling software was developed to merge separate SPECT and multi-slice computed tomography (MSCT) images.
- Lead pearl markers soaked in 99mTc-pertechnetate were used for external localization during imaging.
Findings:
- The integrated SPECT/MSCT 3D model enabled precise visualization and localization of the SNL in all seven BC patients.
- SNL identification and extirpation time were significantly reduced to under 10 minutes per patient.
- The method's accuracy and reproducibility were confirmed by successful gamma probe verification and biopsy.
Implications:
- This cost-effective 3D modeling approach offers a faster, easier, and more accurate alternative to conventional SNL detection methods.
- It provides a valuable tool for healthcare facilities with limited budgets, avoiding the need for expensive hybrid imaging systems.
- The technique has the potential to improve surgical outcomes and reduce healthcare costs in breast cancer management.
