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Related Experiment Video

Updated: Feb 26, 2026

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

Published on: May 15, 2017

Photothermal strain imaging.

Changhoon Choi¹, Joongho Ahn¹, Seungwan Jeon¹

¹Pohang University of Science and Technology, Medical Device Innovation Center, Department of Creative IT Engineering, Pohang, Republic of Korea.

Journal of Biomedical Optics

|July 12, 2017

Summary

This summary is machine-generated.

Photothermal strain imaging (pTSI) uses ultrasound and laser heating to detect lipids within vulnerable plaques, a key factor in cardiovascular disease. This novel technique shows promise for identifying arterial plaque composition and improving cardiovascular diagnostics.

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Last Updated: Feb 26, 2026

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

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Area of Science:

Biomedical Engineering
Medical Imaging
Cardiovascular Research

Background:

Vulnerable plaques are a primary cause of cardiovascular disease.
Detecting lipid content in plaques is crucial for risk assessment.
Conventional intravascular imaging struggles to identify plaque vulnerability effectively.

Purpose of the Study:

To develop and demonstrate a novel imaging technique for detecting lipids in arterial plaques.
To assess the potential of photothermal strain imaging (pTSI) for plaque characterization.

Main Methods:

Photothermal strain imaging (pTSI) was performed using an intravascular ultrasound catheter.
Selective heating of lipids was achieved using a continuous laser source.
A speckle-tracking algorithm analyzed ultrasound B-mode images for strain calculations.

Main Results:

Strain patterns differed significantly between porcine fat and a water-bearing gelatin phantom.
pTSI successfully distinguished between lipid-rich and non-lipid-rich materials.
The technique demonstrated the potential for differentiating lipids within simulated arterial environments.

Conclusions:

Photothermal strain imaging (pTSI) shows promise as a method for detecting lipids in coronary artery plaques.
This technique could enhance the identification of vulnerable plaques, aiding in cardiovascular disease management.
pTSI offers a potential new tool for intravascular imaging and plaque analysis.