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Updated: Feb 26, 2026

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging
Published on: June 21, 2017
Development of low-cost photoacoustic imaging systems using very low-energy pulsed laser diodes
Ali Hariri1, Afreen Fatima2, Nafiseh Mohammadian2
1Wayne State University, Bioengineering Department, Detroit, Michigan, United StatesbUniversity of California, Department of NanoEngineering, San Diego, California, United States.
Abstract:
With the growing application of photoacoustic imaging (PAI) in medical fields, there is a need to make them more compact, portable, and affordable. Therefore, we designed very low-cost PAI systems by replacing the expensive and sophisticated laser with a very low-energy laser diode. We implemented photoacoustic (PA) microscopy, both reflection and transmission modes, as well as PA computed tomography systems. The images obtained from tissue-mimicking phantoms and biological samples determine the feasibility of using a very low-energy laser diode in these configurations.

