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Hybrid Materials and Nanocomposites as Multifunctional Biomaterials
Heveline D M Follmann1, Alliny F Naves2, Rafael A Araujo3
1Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854. United States.
Current Pharmaceutical Design
|July 13, 2017
Summary
Hybrid and nanocomposite biomaterials are crucial for nanomedicine applications like drug delivery and tissue engineering. Optimizing their structure, biocompatibility, and stability is key for effective use.
Area of Science:
- Nanomedicine
- Biomaterials Science
- Materials Chemistry
Background:
- Hybrid and nanocomposite materials are increasingly utilized in nanomedicine.
- These materials offer unique properties due to their nanoscale nature and tunable characteristics.
- Their application spans controlled drug delivery, tissue engineering, biosensors, and theranostic systems.
Purpose of the Study:
- To provide a comprehensive overview of hybrid and nanocomposite biomaterials in nanomedicine.
- To highlight the importance of material property tuning through synthesis and material synergy.
- To discuss fabrication challenges and categorize different types of hybrid nanocomposites.
Main Methods:
- Review of recent literature on hybrid and nanocomposite biomaterials.
- Classification of nanocomposites based on their constituent phases (inorganic/inorganic, organic/organic, organic/inorganic).
- Analysis of applications in drug delivery, tissue engineering, biosensors, and theranostics.
Main Results:
- Hybrid and nanocomposite materials offer versatile platforms for advanced nanomedicine applications.
- Tuning material properties by selecting synthetic methods and achieving synergy is critical.
- Fabrication challenges exist, particularly for hybrid systems combining organic and inorganic phases.
Conclusions:
- Significant advancements in hybrid biomaterials require balancing structure, biocompatibility, and stability.
- Exploiting nanoscale properties is essential for developing effective nanomedicine solutions.
- Further research is needed to overcome fabrication hurdles and optimize performance.
