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Synthesis and beta-adrenoceptor blocking activity of thiophenic analogues of metoprolol
Il Farmaco; Edizione Scientifica
|January 1, 1986
Abstract:
The synthesis of the thiophenic analogue of metoprolol (VI) and of its related compound (VII) are described. Except for cardioselectivity at low doses, the thiophenic analogue of metoprolol behaves in a very similar way as this compound in all the aspects considered in a preliminary pharmacological study.
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