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In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290

Hiroko Shimada1, Quanlong Lu2, Christine Insinna-Kettenhofen2

  • 1Neurobiology-Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Cell Reports
|July 13, 2017
PubMed

Keywords:
Hedgehog signalingJoubert syndromeLCAciliary transition zoneciliogenesisciliopathiesiPSCorganoidprimary ciliaretinal degeneration

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