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Related Experiment Video

Updated: Feb 26, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis

Refined Murine Model of Idiopathic Pulmonary Fibrosis

Published on: June 17, 2025

Idiopathic Pulmonary Fibrosis: A Case Discussion.

Meghan K Felton, Brian Bautista, Lee E Morrow

The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists

|July 14, 2017

Summary

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease. Pharmacists play a key role in managing pirfenidone and nintedanib treatments for IPF patients, ensuring optimal outcomes.

Area of Science:

Pulmonology
Pharmacology

Background:

Idiopathic pulmonary fibrosis (IPF) is a chronic, fatal lung disease marked by progressive pulmonary function decline.
Current therapeutic options for IPF are limited.

Observation:

A case study of a 68-year-old male patient with IPF is presented.
The patient initially received pirfenidone, experiencing significant gastric distress.
Treatment was subsequently transitioned to nintedanib.

Findings:

Pirfenidone and nintedanib are the only FDA-approved medications for IPF in the U.S.
These agents possess unique pharmacological profiles compared to previous IPF therapies.

Implications:

Pharmacists require a comprehensive understanding of IPF treatment guidelines.

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Expertise in drug acquisition, dosing, patient education, and monitoring of pirfenidone and nintedanib is crucial for pharmacists.

Effective pharmacist involvement can enhance therapeutic outcomes for IPF patients.