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Volume Measurement by Diffusion-Weighted Imaging in Cervical Cancer
Shinya Fujii1, Naoki Iwata2, Chie Inoue1
1Division of Radiology, Department of Pathophysiological and Therapeutic Science, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
Yonago Acta Medica
|July 14, 2017
Summary
Diffusion-weighted (DW) imaging offers a valid method for measuring cervical cancer tumor volume. This technique demonstrates excellent reliability, comparable to traditional T2-weighted imaging, aiding in treatment assessment.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Accurate cervical cancer tumor volume measurement is crucial for treatment planning and monitoring.
- Traditional methods rely on T2-weighted imaging, but diffusion-weighted imaging (DW imaging) shows promise for improved volumetric assessment.
Purpose of the Study:
- To evaluate the validity and reliability of tumor volume measurement in cervical cancer using diffusion-weighted (DW) imaging.
- To compare DW imaging-based volume measurements with those obtained from T2-weighted imaging.
Main Methods:
- A retrospective study analyzed 22 patients with cervical cancer who underwent preoperative 3.0 T MRI with DW imaging.
- Tumor volumes were measured manually using T2-weighted imaging and automatically using 3D DW imaging with a volume-rendering algorithm.
- Intraclass correlation coefficient (ICC) and Bland-Altman plots assessed measurement validity and intra-observer variability.
Main Results:
- An excellent ICC (0.962) was found between T2-weighted and DW imaging volume measurements.
- The 95% limits of agreement were -52.7 to 35.7 mL, with a mean difference of -8.5 mL.
- Intra-observer variability showed an excellent ICC (0.963) with 95% limits of agreement from -42.2 to 47.4 mL.
Conclusions:
- Diffusion-weighted (DW) imaging is a valid and reliable method for measuring cervical cancer tumor volume.
- DW imaging provides accurate volumetric data comparable to T2-weighted imaging, supporting its use in clinical practice.
