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RETRACTED ARTICLE: Thyroid nodules update in diagnosis and management
Shrikant Tamhane1, Hossein Gharib2,3
1Endocrinology and Metabolism, Rochester, 55905 MN USA.
Clinical Diabetes and Endocrinology
|July 14, 2017
Summary
Thyroid nodules are common, often found incidentally. This review covers diagnosis, risk, and management, including new molecular tests for thyroid cancer detection.
Area of Science:
- Endocrinology
- Oncology
- Diagnostic Imaging
Background:
- Thyroid nodules are highly prevalent, with increasing detection due to advanced imaging.
- Clinical significance involves excluding malignancy (4-6.5%), assessing function, and managing compressive symptoms.
Purpose of the Study:
- To review current evidence and guidelines for thyroid nodule evaluation and management.
- To address advances, controversies, and the role of new molecular tests in assessing thyroid nodules for cancer.
Main Methods:
- Literature review of current guidelines and supporting evidence.
- Analysis of recent advances in diagnostic and molecular testing for thyroid nodules.
Main Results:
- The review synthesizes information on differential diagnosis, risk stratification, and treatment strategies.
- Discusses the integration and controversies surrounding new molecular tests in clinical practice.
Conclusions:
- Evidence-based strategies are crucial for managing the high prevalence of thyroid nodules.
- Molecular tests offer new avenues for thyroid nodule assessment, requiring careful consideration within current management frameworks.

