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Updated: Feb 26, 2026

Development of Metarhizium anisopliae as a Mycoinsecticide: From Isolation to Field Performance
Published on: July 30, 2017
Fungal keratitis caused by Metarhizium anisopliae complex
Mahmood J Showail1,2, Julianne V Kus3,4, George Kar Tsui3
1The Department of Ophthalmology and Vision Sciences, University of Toronto, 340 College Street, Suite 400, Toronto, ON, Canada M5T 3A9.
Purpose:
To report a case of fungal keratitis caused by Metarhizium anisopliae complex.
Methods:
Case report.
Results:
Our patient presented with a central corneal infiltrate. Fungal culture yielded a Metarhizium species. She was started on antifungal agents with no significant improvement. A therapeutic corneal transplant was performed after perforation. At two years follow up, she was free of infection.
Conclusion:
Metarhizium anisopliae is a very rare cause of keratitis. Although previous reported cases showed clinical improvement with antifungal agents, this case required surgical treatment to control the infection.
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