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Cough syncope induced by post nasal drip successfully managed by Gabapentin.

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A rare case of cough syncope, triggered by chronic postnasal drip, was effectively managed with a low dose of Gabapentin. This finding suggests a new treatment avenue for refractory chronic cough and associated syncope.

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Area of Science:

  • Neurology
  • Pulmonology
  • Pharmacology

Background:

  • Syncope, a transient loss of consciousness, is a frequent neurological and emergency department complaint.
  • Cough syncope, a specific type, can be debilitating and often misdiagnosed.
  • Chronic intractable cough, often from postnasal drip, can precipitate syncope.

Observation:

  • A case report details a patient experiencing debilitating cough syncope due to chronic postnasal drip.
  • The patient's symptoms were significantly controlled with a low dose of Gabapentin.
  • This dosage is considerably lower than those typically used for neuropathic pain or epilepsy.

Findings:

  • Low-dose Gabapentin demonstrated significant efficacy in managing cough syncope.
  • Gabapentin offers a potential therapeutic option for chronic cough refractory to standard treatments.
  • This case highlights the importance of considering cough syncope in patients with unexplained syncope and chronic cough.

Implications:

  • Pulmonologists should consider Gabapentin for refractory chronic cough, especially when associated with syncope.
  • Further research is warranted to validate the effectiveness of low-dose Gabapentin in chronic cough management.
  • This approach may reduce the need for extensive and costly investigations associated with syncope.