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A Fully Implantable, NFC Enabled, Continuous Interstitial Glucose Monitor.

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This study introduces an integrated system-on-chip for a long-term, implantable continuous glucose monitor. The device harvests energy wirelessly and transmits glucose data, enabling passive monitoring.

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Area of Science:

  • Biomedical Engineering
  • Electrical Engineering
  • Materials Science

Background:

  • Continuous glucose monitoring (CGM) is crucial for diabetes management.
  • Existing CGM systems often require frequent battery replacements or invasive procedures.
  • There is a need for long-term, implantable, and passive monitoring solutions.

Purpose of the Study:

  • To develop an integrated system-on-chip (SoC) for a fully implantable, battery-assisted, passive continuous glucose monitor (CGM).
  • To enable long-term, continuous glucose level tracking with minimal user intervention.
  • To validate the system's functionality through post-layout simulations.

Main Methods:

  • Integration of an amperometric glucose sensor interface, a near field communication (NFC) wireless front-end, and a digital switched-mode power management unit.
  • Utilizing the 13.56 MHz Industrial, Scientific, and Medical (ISM) band for energy harvesting and data backscattering.
  • Implementation in 14nm CMOS technology.

Main Results:

  • Successful integration of key components for a passive CGM system.
  • Demonstrated capability for wireless energy harvesting and data transmission via NFC.
  • Post-layout simulations confirmed the system's operational viability.

Conclusions:

  • The developed SoC is a viable core for a long-term, fully implantable, passive CGM.
  • The system offers a promising approach for unobtrusive and continuous glucose monitoring.
  • Further development could lead to improved diabetes management through advanced wearable technology.