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Comparison of rice water, rice electrolyte solution, and glucose electrolyte solution in the management of infantile

PubMed

Insights

Rice water (RW) and rice-based electrolyte solutions (RES) effectively treat acute gastroenteritis in infants. These rice-based treatments outperformed the World Health Organization's glucose electrolyte solution (GES) in reducing stool output and promoting weight gain.

Area of Science:

  • Pediatrics
  • Gastroenterology
  • Nutrition

Background:

  • Acute gastroenteritis is a common cause of dehydration in infants.
  • Oral rehydration therapy is the standard treatment for dehydration.
  • Existing oral rehydration solutions may have limitations.

Purpose of the Study:

  • To compare the efficacy of rice water (RW) and rice-based electrolyte solution (RES) against the World Health Organization's (WHO) glucose electrolyte solution (GES) for treating acute gastroenteritis in infants.
  • To evaluate the impact of these treatments on hydration status, stool output, and biochemical markers.

Main Methods:

  • A randomized controlled trial involving 150 infants under 6 months with acute gastroenteritis.
  • Infants were treated with RW, RES, or GES.
  • Hydration status, stool characteristics, and biochemical variables (serum electrolytes, blood urea nitrogen, serum creatinine) were monitored before and after 48 hours of treatment.

Main Results:

  • No significant difference in initial hydration status or biochemical markers among the groups.
  • RW and RES groups showed significantly lower blood urea nitrogen and serum creatinine levels after 48 hours compared to the GES group (p < 0.05).
  • RW and RES were superior to GES in reducing stool frequency and volume, and in promoting weight gain. Serum potassium was lower in the RW group than in the RES group.

Conclusions:

  • Rice water and rice-based electrolyte solutions are effective and potentially superior alternatives to glucose electrolyte solutions for oral rehydration in infants with acute gastroenteritis.
  • These rice-based solutions may offer benefits in reducing dehydration markers and improving nutritional status.
  • Further research into the optimal composition and use of rice-based oral rehydration solutions is warranted.

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