Related Experiment Video
Updated: Feb 26, 2026

Innervation of Human Intestinal Organoids
Published on: January 17, 2025
[Adult intestinal no rotation]
Insights
Intestinal malrotation, typically seen in infants, can cause intestinal obstruction in adults. This case highlights a rare adult presentation of malrotation, successfully treated with Ladd's procedure.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Pediatric Surgery
Background:
- Intestinal malrotation is a congenital anomaly where intestines fail to rotate properly during fetal development.
- It predominantly affects infants, with 90% of intestinal obstruction cases occurring before one year of age.
- Adult presentations of intestinal malrotation leading to obstruction are exceedingly rare.
Observation:
- A 27-year-old female presented with severe abdominal pain, vomiting, distention, dehydration, and malnutrition.
- Initial management included esophagogastroduodenoscopy (EGDS) and CT scan, followed by a 48-hour clinical observation period.
- Surgical intervention was deemed necessary due to a diagnosis of high intestinal obstruction.
Findings:
- Intraoperative findings revealed a complete absence of intestinal rotation, confirming intestinal malrotation.
- The patient underwent Ladd's procedure, a surgical technique to correct intestinal malrotation.
- A prophylactic appendectomy was also performed during the surgery.
Implications:
- This case underscores the importance of considering intestinal malrotation in adult patients presenting with symptoms of high intestinal obstruction.
- Successful surgical management with Ladd's technique in this adult patient demonstrates its efficacy beyond pediatric cases.
- The rarity of this condition in adults warrants increased awareness among clinicians for timely diagnosis and intervention.
Abstract:
90% of cases of intestinal obstruction caused by intestinal malrotation occur in children under 1 year of age, being very uncommon in adults. A female patient of 27 years of age consults with abdominal pain, vomiting, abdominal distention, dehydration and signs of severe malnutrition. After EGDS, CT scan, and 48 hours of clinical expectation, surgical intervention was decided with diagnosis of high intestinal obstruction. Intraoperative finding was no intestinal rotation at all. Ladd´s technique was performed together with prophylactic appendectomy. Postoperative evolution was favorable. The rare presentation in adults motivates the presentation of this case.
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