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Mild cognitive impairment in type 2 diabetes mellitus and related risk factors: a review

Xiao-Ying Yuan1, Xu-Gang Wang1

  • 1.

Reviews in the Neurosciences
|July 14, 2017
PubMed

Insights

Type 2 diabetes mellitus (T2DM) is linked to higher rates of mild cognitive impairment (MCI). Factors like blood sugar issues and diabetic complications contribute to cognitive decline in T2DM patients.

Area of Science:

  • Endocrinology
  • Neurology
  • Gerontology

Background:

  • Type 2 diabetes mellitus (T2DM) is a global health issue.
  • Mild cognitive impairment (MCI) is more prevalent in T2DM patients.
  • Cognitive changes can impact daily functioning.

Purpose of the Study:

  • To systematically review risk factors for cognitive impairment in T2DM.
  • To understand the link between T2DM and cognitive decline.
  • To highlight the need for further research and early intervention.

Main Methods:

  • Systematic overview of existing studies.
  • Analysis of risk factors associated with T2DM and cognitive impairment.
  • Literature review focusing on pathoglycemia, diabetic complications, and other contributing factors.

Main Results:

  • Individuals with T2DM exhibit a higher incidence of MCI.
  • Altered pathoglycemia, diabetic complications, and related end products are implicated.
  • Physical and psychological status are significant risk factors for cognitive impairment in T2DM.

Conclusions:

  • The pathophysiology of MCI in T2DM requires further elucidation.
  • Identifying and treating early signs of cognitive impairment in T2DM is crucial.
  • High-quality studies and effective treatments are needed for T2DM-related cognitive issues.
Keywords:
Alzheimer’s disease (AD)mild cognitive impairment (MCI)risk factortype 2 diabetes mellitus (T2DM)

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