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Related Experiment Video

Updated: Feb 26, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
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Regular moist snuff dipping does not affect endurance exercise performance.

Frida Björkman1, Fredrik Edin2, C Mikael Mattsson1,3

  • 1Åstrand Laboratory of Work Physiology, The Swedish School of Sport and Health Sciences, Stockholm, Sweden.

Plos One
|July 14, 2017
PubMed
Summary
This summary is machine-generated.

Quitting daily snuff use for over six weeks significantly lowers resting heart rate and blood pressure. Snuff cessation also impacts cholesterol levels, indicating reversible cardiovascular effects from long-term use.

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Area of Science:

  • Physiology
  • Cardiovascular Health
  • Tobacco Use Research

Background:

  • Previous studies on snuff's physiological effects used cross-sectional designs or non-tobacco users.
  • The impact of discontinuing long-term, daily snuff use on physiological markers was previously unknown.

Purpose of the Study:

  • To investigate the physiological and cardiovascular effects of snuff cessation after prolonged daily use.
  • To compare changes in participants who stopped using snuff versus a control group who continued.

Main Methods:

  • 24 participants with >2 years of daily snuff use underwent testing before and after >6 weeks of cessation.
  • A control group (11 participants) continued their normal snuff habits.
  • Measurements included resting and exercise heart rate, blood pressure, body mass, cholesterol, and other metabolic markers.

Main Results:

  • Snuff cessation led to significantly lower resting heart rate and blood pressure, and increased body mass.
  • Total cholesterol and LDL increased significantly in the cessation group compared to controls.
  • Submaximal exercise heart rate and blood pressure were reduced post-cessation, while endurance performance metrics remained unchanged.

Conclusions:

  • Endurance exercise performance is not affected by prolonged snuff use.
  • Cardiovascular risk factors show contradictory effects, but heart rate and blood pressure during rest and submaximal exercise decrease after snuff cessation.
  • The adrenergic stress on circulation from long-term snuff use appears to be reversible.