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Effect of Modic Changes in Cervical Degenerative Disease
Kyung Tag Kang1, Dong Wuk Son1, Oik Kwon1
1Department of Neurosurgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Korean Journal of Spine
|July 14, 2017
Summary
Modic changes in the cervical spine are linked to worse degenerative conditions and a higher likelihood of needing anterior cervical discectomy with fusion (ACDF) surgery.
Area of Science:
- Radiology
- Orthopedics
- Spine Surgery
Background:
- Modic changes represent bone marrow signal alterations on MRI.
- Research on Modic changes in the cervical spine is limited.
- Cervical degenerative disease impacts a significant patient population.
Purpose of the Study:
- To investigate the association between cervical degenerative disease and Modic changes.
- To analyze Modic change characteristics in the cervical spine.
- To evaluate the clinical implications of Modic changes in cervical spine disorders.
Main Methods:
- Retrospective analysis of 169 patients with neck pain.
- Radiological assessment of disc herniation grade, disc space height, and cervical lordosis.
- Evaluation of Modic change type, vertebral level, and surgical requirement.
Main Results:
- Modic changes were present in 66 patients, predominantly Type II at C5-6.
- Patients with Modic changes exhibited worse disc herniation grade, reduced disc space height, and poorer cervical lordosis.
- Modic changes were associated with a significantly higher incidence of anterior cervical discectomy with fusion (ACDF).
Conclusions:
- Modic changes are indicative of cervical degenerative processes.
- The presence of Modic changes correlates with increased need for ACDF.

