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Related Experiment Videos

Methamphetamine-Related Disorders.

Euphrosyne Gouzoulis-Mayfrank1, Roland Härtel-Petri, Willem Hamdorf

  • 1*All of the authors of the S3 guideline are listed in eTable1. They contributed equally to this article; Landschaftsverband Rheinland (Rhineland Regional Council, LVR)-Klinik Köln; Psychotherapeutic Practice Bayreuth; Allgemeine Hospitalgesellschaft (AHG) Klinik Mecklenburg; University Medical Center Göttingen; Technische Universität Chemnitz; Department of Psychiatry and Psychotherapy, University Hospital of Regensburg.

Deutsches Arzteblatt International
|July 15, 2017
PubMed
Summary
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Treatment guidelines for methamphetamine use disorder are lacking. Evidence supports psychotherapy and exercise programs, but pharmacotherapy shows limited efficacy, with only weak recommendations for specific medications.

Area of Science:

  • Addiction Medicine
  • Neuroscience
  • Psychiatry

Background:

  • Methamphetamine poses significant risks, including acute complications, neurotoxicity, and dependence.
  • Existing treatment guidelines for methamphetamine use disorder are scarce globally and in Germany.

Purpose of the Study:

  • To develop evidence-based recommendations for treating methamphetamine-related disorders.
  • To address the lack of established treatment protocols in the field.

Main Methods:

  • A systematic literature search was conducted on methamphetamine use disorder treatments.
  • A multidisciplinary expert panel formulated recommendations using the nominal group technique.

Main Results:

  • The evidence base for methamphetamine use disorder treatment is limited.

Related Experiment Videos

  • Cognitive behavioral therapy, contingency management, and structured exercise programs show efficacy.
  • Pharmacotherapy demonstrated minimal effectiveness, with weak recommendations for tranquilizers and atypical antipsychotics; sertraline is contraindicated.

    • Conclusions:

    • Recommendations often carry a weak grade due to limited evidence and modest effect sizes.
    • Symptom-oriented treatment is advised for acute situations.
    • Psychotherapy and structured exercise programs are recommended interventions.