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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
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[Fungal sinusitis].

E Lafont1, C Aguilar1, P Vironneau2

  • 1Service maladies infectieuses et tropicales, hôpital Necker-Enfants-Malades, institut Imagine, université Paris Descartes, Assistance publique-Hôpitaux de Paris, 149, rue de Sèvres, 75743 Paris, France.

Revue Des Maladies Respiratoires
|July 15, 2017
PubMed
Summary
This summary is machine-generated.

Fungal sinusitis, though rare, presents diverse forms impacting immunocompromised and immunocompetent individuals. Diagnosis involves imaging and biopsies, guiding treatment with surgery and antifungals for effective management.

Keywords:
ChampignonsDiagnosisDiagnosticFungiSinusiteSinusitisTraitementTreatment

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Area of Science:

  • Otolaryngology
  • Mycology
  • Infectious Diseases

Background:

  • Sinusitis is common, affecting 20% of the population, but fungal sinusitis is a rare complication.
  • Fungal sinusitis encompasses a spectrum of disorders, including acute/chronic and invasive/non-invasive presentations.
  • Aspergillus species are the most common fungal pathogens implicated in fungal sinusitis.

Purpose of the Study:

  • To differentiate between various forms of fungal sinusitis.
  • To outline diagnostic approaches for fungal sinusitis.
  • To describe treatment strategies for invasive and non-invasive fungal sinusitis.

Main Methods:

  • Diagnosis relies on radiological examination (e.g., CT scans, MRI).
  • Endoscopy with mucosal biopsies is crucial for histological and mycological analysis.
  • Distinguishing between invasive, non-invasive, and allergic forms guides therapeutic decisions.

Main Results:

  • Invasive fungal sinusitis typically affects immunocompromised or diabetic patients.
  • Non-invasive fungal sinusitis occurs in immunocompetent individuals with chronic, antibiotic-resistant symptoms.
  • Allergic fungal sinusitis is linked to host hypersensitivity to fungal elements.

Conclusions:

  • Accurate diagnosis through imaging, endoscopy, and biopsy is essential for classifying fungal sinusitis.
  • Non-invasive fungal sinusitis management often requires surgical intervention, potentially with adjunctive antifungal and anti-inflammatory therapies.
  • Invasive fungal sinusitis necessitates systemic antifungal treatment, with surgical consideration for specific types like mucormycosis.