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Genome Sequence of Oxalobacter formigenes Strain OXCC13
Marguerite Hatch1, Milton J Allison2, Fahong Yu3
1Department of Pathology, Immunology and Laboratory Medicine, University of Florida, College of Medicine, Gainesville, Florida, USA hatchma@ufl.edu.
Oxalobacter formigenes, a gut bacterium, is crucial for oxalate homeostasis and preventing kidney stones. This study presents the genome sequence of a human-derived O. formigenes strain, OXCC13, aiding future research into its role in kidney stone prevention.
Area of Science:
- Microbiology
- Genomics
- Human Health
Background:
- Oxalobacter formigenes plays a key role in oxalate homeostasis.
- Lack of O. formigenes colonization is a risk factor for kidney stone formation.
- Understanding O. formigenes is vital for developing strategies against kidney stones.
Purpose of the Study:
- To present the genome sequence of a human O. formigenes strain.
- To provide a genomic resource for O. formigenes research.
- To facilitate studies on oxalate metabolism and kidney stone prevention.
Main Methods:
- Genome sequencing of O. formigenes strain OXCC13.
- Bioinformatic analysis of the obtained genome sequence.
Main Results:
- The complete genome sequence of O. formigenes OXCC13 was determined.
- The genome provides insights into the metabolic capabilities of O. formigenes.
Conclusions:
- The genome sequence of O. formigenes OXCC13 is a valuable resource.
- This genomic data can advance research on gut microbiota and kidney stone disease.
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