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First Draft Genome for a Burkholderia mallei Isolate Originating from a Glanderous Mule from Brazil

G Girault1, C Woudstra2, B Martin1

  • 1University Paris-Est, Anses, Animal Health Laboratory, Bacterial Zoonoses Unit, Maisons-Alfort, France.

Genome Announcements
|July 15, 2017
PubMed

Insights

This study presents the first genome sequence of Burkholderia mallei, the bacteria causing glanders, from a strain isolated in Brazil. This provides a crucial genomic resource for understanding glanders in the Americas.

Area of Science:

  • Microbiology
  • Genomics
  • Veterinary Medicine

Background:

  • * Burkholderia mallei is the causative agent of glanders, a highly contagious zoonotic disease affecting equids.
  • * Glanders poses a significant threat to animal health and has implications for public health.
  • * Genomic data is essential for understanding bacterial pathogenesis and developing control strategies.

Purpose of the Study:

  • * To present the draft genome sequence of Burkholderia mallei strain 16-2438_BM#8.
  • * To provide the first genomic resource for a Burkholderia mallei strain isolated from the American continent.

Main Methods:

  • * Whole-genome sequencing of Burkholderia mallei strain 16-2438_BM#8.
  • * Bioinformatic analysis of the resulting draft genome sequence.

Main Results:

  • * A draft genome sequence for Burkholderia mallei strain 16-2438_BM#8 was successfully generated.
  • * This represents the first publicly available genome sequence of a Burkholderia mallei strain originating from South America.

Conclusions:

  • * The availability of this genome sequence enhances our understanding of Burkholderia mallei diversity.
  • * This genomic data will facilitate future research on glanders epidemiology and control in the Americas.

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