Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

41.1K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.1K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

15.9K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.9K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

775
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
775
Next-generation Sequencing03:00

Next-generation Sequencing

99.4K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
99.4K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

3.5K
3.5K
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

49.2K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
49.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterizing the nasopharyngeal microbiome and resistome of dairy cattle with and without bovine respiratory disease.

Microbiology spectrum·2026
Same author

Apparent expansion of virulent <i>Vibrio parahaemolyticus</i> in humans and sea otters.

Virulence·2025
Same author

Co-Occurrence Patterns of Bacterial Communities and Resistance Genes: A Comprehensive Multi-Pen Fecal Microbiome and Resistome Study in Dairy Farms.

Microorganisms·2025
Same author

<i>Fusobacterium nucleatum</i> and Its Impact on Colorectal Cancer Chemoresistance: A Meta-Analysis of In Vitro Co-Culture Infections.

Cancers·2025
Same author

Comparison of virulence and resistance genes in <i>Mannheimia haemolytica</i> and <i>Pasteurella multocida</i> from dairy cattle with and without bovine respiratory disease.

Microbiology spectrum·2025
Same author

Case Report: Shift from Aggressive Periodontitis to Feline Chronic Gingivostomatitis Is Linked to Increased Microbial Diversity.

Pathogens (Basel, Switzerland)·2025

Related Experiment Video

Updated: Feb 26, 2026

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions
14:58

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

Published on: March 5, 2022

4.9K

100K Pathogen Genome Project.

Bart C Weimer1

  • 1Department of Population Health and Reproduction, School of Veterinary Medicine, UC Davis, Davis, California, USA bcweimer@ucdavis.edu.

Genome Announcements
|July 15, 2017
PubMed
Summary
This summary is machine-generated.

The 100K Pathogen Genome Project generates diverse pathogen genome sequences, creating a global database for applications in systematics and public health.

More Related Videos

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

11.7K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.8K

Related Experiment Videos

Last Updated: Feb 26, 2026

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions
14:58

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

Published on: March 5, 2022

4.9K
A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

11.7K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.8K

Area of Science:

  • Microbiology
  • Genomics
  • Bioinformatics

Background:

  • Pathogen genomes are crucial for understanding infectious diseases.
  • Global surveillance of pathogens requires comprehensive genomic data.

Purpose of the Study:

  • To produce draft and closed genome sequences from a diverse range of pathogens.
  • To establish a global bacterial genome diversity snapshot.
  • To create a versatile sequence database for scientific and public health applications.

Main Methods:

  • Genome sequencing of diverse pathogens.
  • Global data collection and integration.
  • Database development and curation.

Main Results:

  • Generation of draft and closed genome sequences for numerous pathogens.
  • Compilation of a comprehensive database reflecting global bacterial genome diversity.
  • Demonstration of the database's utility in systematics and public health.

Conclusions:

  • The 100K Pathogen Genome Project successfully created a valuable genomic resource.
  • The generated database supports diverse applications, from evolutionary studies to disease outbreak investigations.