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Updated: Feb 26, 2026

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
Published on: August 2, 2012
Versatile control of the submolecular motion of di(acylamino)pyridine-based [2]rotaxanes
Alberto Martinez-Cuezva1, Aurelia Pastor1, Giacomo Cioncoloni2
1Departamento de Química Orgánica , Facultad de Química , Regional Campus of International Excellence "Campus Mare Nostrum" , Universidad de Murcia , E-30100 , Murcia , Spain .
Abstract:
A cyclic network of chemical reactions has been conceived for exchanging the dynamic behaviour of di(acylamino)pyridine-based rotaxanes and surrogates. X-ray diffraction studies revealed the intercomponent interactions in these interlocked compounds and were consistent with those found in solution by dynamic NMR experiments. This particular binding site was incorporated into a molecular shuttle enabled for accessing two states with an outstanding positional discrimination through chemical manipulation. Furthermore, the ability of the di(acylamino)pyridine domain to associate with external binders with a complementary array of HB donor and acceptor sites was exploited for the advance of an unprecedented electrochemical switch operating through a reversible anion radical recognition process.
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