Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

344
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
344
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

945
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
945
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

736
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
736
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

680
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
680
Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

629
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
629
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

739
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
739

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gaps in the Outpatient Referral Cascade for Patients With Medicaid.

JAMA network open·2025
Same author

Effectiveness of Virtual Care Team Guided Management of Hospitalized Patients with HFrEF by Ethnicity.

Journal of cardiac failure·2024
Same author

High Mortality With COVID-19 Acute Pericarditis.

Journal of the American Heart Association·2023
Same author

Virtual Care Team Guided Management of Patients With Heart Failure During Hospitalization.

Journal of the American College of Cardiology·2023
Same author

Investigating the Association Between Telemedicine Use and Timely Follow-Up Care After Acute Cardiovascular Hospital Encounters.

JACC. Advances·2023
Same author

Association of Myocardial Blood Flow Reserve With Adverse Left Ventricular Remodeling in Patients With Aortic Stenosis: The Microvascular Disease in Aortic Stenosis (MIDAS) Study.

JAMA cardiology·2021

Related Experiment Video

Updated: Feb 26, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

1.1K

Non-functional tricuspid valve disease.

Dale S Adler1

  • 1Division of Cardiovascular Diseases, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.

Annals of Cardiothoracic Surgery
|July 15, 2017
PubMed
Summary
This summary is machine-generated.

Non-functional tricuspid regurgitation stems from direct valve damage, unlike functional TR. Early identification and monitoring are crucial for managing this severe condition and preventing poor outcomes.

Keywords:
Tricuspid valveisolated tricuspid valve surgeryright heart failuretricuspid annulustricuspid regurgitation

More Related Videos

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

3.2K
Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

4.4K

Related Experiment Videos

Last Updated: Feb 26, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

1.1K
Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

3.2K
Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

4.4K

Area of Science:

  • Cardiology
  • Cardiac Surgery

Background:

  • Severe tricuspid regurgitation (TR) is often functional, linked to pulmonary hypertension or right ventricular dysfunction.
  • A significant portion of severe TR is non-functional, arising from primary valve damage independent of right ventricular issues.

Purpose of the Study:

  • To differentiate between functional and non-functional severe tricuspid regurgitation.
  • To highlight the diverse etiologies and clinical implications of non-functional TR.
  • To emphasize the importance of vigilant monitoring in patients with severe non-functional TR.

Main Methods:

  • Review of etiologies causing direct tricuspid valve damage.
  • Analysis of the progression from non-functional to functional TR.
  • Emphasis on echocardiographic quantification and clinical assessment for patient management.

Main Results:

  • Non-functional TR arises from various conditions including rheumatic disease, endocarditis, and iatrogenic causes.
  • Initially non-functional TR can progress to functional TR due to secondary right ventricular dysfunction.
  • Late-stage interventions for severe TR carry high mortality risks.

Conclusions:

  • Non-functional severe tricuspid regurgitation requires careful monitoring of valve function, right ventricular status, and patient symptoms.
  • Prompt diagnosis and management are essential to mitigate morbidity and mortality associated with severe TR.
  • Echocardiography and clinical evaluation are key to managing patients with non-functional severe tricuspid regurgitation.