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Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
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Primary osteosarcoma of the breast: a case report
Chan Seok Yoon1, Sung Soo Kang1
1Department of Surgery, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea.
Annals of Surgical Treatment and Research
|July 15, 2017
Summary
Primary osteosarcoma of the breast is rare. This case highlights diagnosis and surgical management of this uncommon breast cancer, emphasizing wide excision without adjuvant therapy.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Primary osteosarcoma of the breast is an extremely rare malignancy.
- Distinguishing it from other breast masses can be challenging due to varied presentations.
Observation:
- A 77-year-old woman presented with a palpable, hard mass in her right breast.
- Mammography and ultrasound revealed a calcified, round-shaped mass with indeterminate features.
Findings:
- Excisional biopsy confirmed the diagnosis of primary osteosarcoma of the breast.
- Staging with PET-CT and bone scan ruled out metastatic disease or primary bone involvement.
Implications:
- Wide local excision is a primary treatment modality for localized primary breast osteosarcoma.
- Adjuvant chemotherapy and radiation therapy may not be necessary in all cases, warranting further investigation into optimal treatment protocols.

