Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

2.1K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.1K
Cancer Vaccines01:30

Cancer Vaccines

1.2K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.2K
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

297
Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
297
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

442
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
442
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

3.9K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.9K
Cancer Therapies02:49

Cancer Therapies

10.3K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Educational Interventions in Oral Hygiene for Patients Undergoing Head and Neck Cancer Radiotherapy: A Feasibility Study.

Journal of cancer education : the official journal of the American Association for Cancer Education·2026
Same author

Evolving Principles for Oral Squamous Cell Carcinoma Screening Programs.

Cancers·2026
Same author

Long-Term Clinical Consequences of Severe Oral Mucositis in Survivors of Lip, Oral Cavity, and Pharynx Cancer Versus Leukemia: A Propensity-Score-Matched Comparative Cohort Study Using Real-World Data.

Medical sciences (Basel, Switzerland)·2026
Same author

Essential oral health competencies for cancer care: standardizing dental education for modern practice.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

Taking Care of Your Mouth During Cancer Treatment.

JAMA oncology·2026
Same author

Dentists' knowledge and practices in supportive care: a French national survey.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026

Related Experiment Video

Updated: Feb 26, 2026

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
12:55

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

Published on: February 16, 2015

22.1K

Supportive care for patients undergoing immunotherapy.

Bernardo Leon Rapoport1,2, Ronwyn van Eeden3, Vincent Sibaud4,5

  • 1The Medical Oncology Centre of Rosebank, 129 Oxford Road, Saxonwold 2196, Johannesburg, South Africa. brapoport@rosebankoncology.co.za.

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
|July 15, 2017
PubMed
Summary
This summary is machine-generated.

Immune checkpoint inhibitors offer new cancer treatment options but cause unique immune-related adverse events (irAEs). Prompt recognition and management of these irAEs are crucial for patient safety and treatment success.

Keywords:
Anti-CTLA-4Anti-PD-1Anti-PDL-1ColitisEndocrinopathyImmune checkpoint inhibitorsImmune-related adverse eventsNephritisPneumonitisSkin rashVitiligoirAE

More Related Videos

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

15.6K
A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

30.6K

Related Experiment Videos

Last Updated: Feb 26, 2026

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
12:55

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

Published on: February 16, 2015

22.1K
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

15.6K
A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

30.6K

Area of Science:

  • Oncology
  • Immunology
  • Pharmacology

Background:

  • Immune checkpoint inhibitors (ICIs) represent a novel class of anti-cancer therapeutics.
  • ICIs, including anti-CTLA-4 and anti-PD-1 antibodies, are increasingly utilized in managing various malignancies such as melanoma and non-small cell lung cancer (NSCLC).

Framework:

  • A workshop focused on ICI mechanisms, clinical applications, and associated toxicities.
  • Key topics included skin, gastrointestinal, oral, pulmonary, and endocrinological toxicities, as well as immune-related infections.

Implementation:

  • ICI toxicities, termed immune-related adverse events (irAEs), present uniquely compared to traditional chemotherapy.
  • Current management strategies for irAEs are largely based on symptomatic treatment from ongoing clinical trials, lacking prospective data.

Implications:

  • Oncologists must be vigilant for subtle irAE presentations and distinct management approaches.
  • While often manageable, irAEs can be severe, life-threatening, or fatal if not promptly and correctly treated.
  • The MASCC workshop provided insights into irAEs across organ systems, clinical presentations, and management recommendations.