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Perspectives on Neuroscience
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Perspective: Neuroregenerative Nutrition.

Dennis A Steindler1,2, Brent A Reynolds3

  • 1Neuroscience and Aging Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, and dennis.steindler@tufts.edu.

Advances in Nutrition (Bethesda, Md.)
|July 16, 2017
PubMed
Summary
This summary is machine-generated.

Nutrition is key for maintaining brain health and function as we age. Targeted nutritional interventions can support the body's regenerative capacity, aiding in combating age-related decline and disease.

Keywords:
age- and disease-related inflammationavatar modelscombination nutrient therapiesnutritionregenerative medicinestem cells

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Area of Science:

  • Gerontology and Regenerative Medicine
  • Neuroscience and Immunology
  • Nutritional Science

Background:

  • Aging impairs cellular and organ function, challenging the body's regenerative capacity and homeostasis.
  • While diet supports cellular fitness, it's insufficient for aged systems facing declining regenerative function.
  • Tissue-specific stem cells, including neural stem cells in the brain, are crucial for regeneration but are affected by aging.

Purpose of the Study:

  • To explore the intersection of nutrition and regenerative medicine for aging brains.
  • To propose how diet and nutrition can enhance standard and integrated medical care for age-related brain conditions.
  • To highlight the therapeutic potential of nutrition in maintaining brain health and function throughout the lifespan.

Main Methods:

  • Review and synthesis of current research on nutrition, aging, and regenerative medicine.
  • Integration of findings from immunology, neurodegenerative disease, and cancer research.
  • Proposal of nutritional interventions to support brain regenerative units.

Main Results:

  • The discovery of stem cells in various organs, including the brain, opens avenues for regenerative medicine.
  • Nutrition's influence on regulatory mechanisms and therapeutic potential in regenerative medicine is underexplored.
  • A strong link exists between brain regenerative medicine and nutrition.

Conclusions:

  • Nutritional interventions can maintain optimal functioning of regenerative units during aging.
  • Diet and nutrition can play a primary role in therapeutic treatments for injuries and diseases, especially in later life.
  • Targeted nutrition is essential for supporting brain health and function as the population ages.