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Updated: Feb 26, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

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Integrative Approaches to Understanding the Pathogenic Role of Genetic Variation in Rheumatic Diseases

Vincent A Laufer1, Jake Y Chen2, Carl D Langefeld3

  • 1Division of Clinical Immunology and Rheumatology, School of Medicine, University of Alabama at Birmingham, 1720 2nd Avenue South, SHEL 236, Birmingham, AL 35294-2182, USA.

Rheumatic Diseases Clinics of North America
|July 17, 2017
PubMed

Keywords:
GWASGeneticsIntegrative genomicsPrecision medicineRheumatic diseaseSystems biology

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