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[Congenital heart disease mortality in Spain during a 10 year period (2003-2012)]
Javier Pérez-Lescure Picarzo1, Margarita Mosquera González2, Pello Latasa Zamalloa3
1Cardiología Infantil, Área de Pediatría y Neonatología, Hospital Universitario Fundación Alcorcón, Alcorcón (Madrid), España.
Insights
Congenital heart disease remains a significant cause of infant mortality in Spain, with rates remaining constant over a decade. Certain severe congenital heart conditions, like hypoplastic left heart syndrome, show particularly high mortality rates.
Area of Science:
- Pediatrics
- Cardiology
- Public Health
Background:
- Congenital heart disease (CHD) is a leading cause of infant mortality in developed nations.
- No prior national-level studies in Spain have comprehensively analyzed CHD-related infant mortality.
- Understanding national mortality trends is crucial for public health interventions.
Purpose of the Study:
- To analyze infant mortality rates associated with congenital heart disease in Spain.
- To determine the lethality of specific types of congenital heart disease.
- To examine trends in CHD mortality over a ten-year period (2003-2012).
Main Methods:
- Retrospective observational study utilizing the minimum basic data set.
- Inclusion of infants under one year old diagnosed with congenital heart disease.
- Estimation of mortality rates and relative risk using Poisson regression.
Main Results:
- 2,970 infant deaths (4.58%) occurred in 64,831 patients with CHD.
- The infant mortality rate for CHD was 6.23 per 10,000 live births, remaining constant.
- Hypoplastic left heart syndrome (41.4%), interruption of aortic arch (20%), and total anomalous pulmonary drainage (16.8%) had the highest mortality rates.
Conclusions:
- Congenital heart disease remains a major, unvarying cause of infant mortality in Spain.
- The proportion of infant deaths due to CHD in Spain is comparable to other developed countries.
- Despite medical advancements, specific congenital heart conditions continue to present high mortality risks.
Introduction And Objectives:
Congenital heart disease is a major cause of infant mortality in developed countries. In Spain, there are no publications at national level on mortality due to congenital heart disease. The aim of this study is to analyse mortality in infants with congenital heart disease, lethality of different types of congenital heart disease, and their variation over a ten-year period.
Methods:
A retrospective observational study was performed to evaluate mortality rate of children under one year old with congenital heart disease, using the minimum basic data set, from 2003 to 2012. Mortality rate and relative risk of mortality were estimated by Poisson regression.
Results:
There were 2,970 (4.58%) infant deaths in a population of 64,831 patients with congenital heart disease, with 73.8% of deaths occurring during first week of life. Infant mortality rate in patients with congenital heart disease was 6.23 per 10,000 live births, and remained constant during the ten-year period of the study, representing 18% of total infant mortality rate in Spain. The congenital heart diseases with highest mortality rates were hypoplastic left heart syndrome (41.4%), interruption of aortic arch (20%), and total anomalous pulmonary drainage (16.8%). Atrial septal defect (1%) and pulmonary stenosis (1.1%) showed the lowest mortality rate.
Conclusions:
Congenital heart disease was a major cause of infant mortality with no variations during the study period. The proportion of infants who died in our study was similar to other similar countries. In spite of current medical advances, some forms of congenital heart disease show very high mortality rates.
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