Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

1.8K
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
1.8K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.2K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.2K
Bone Disorders01:29

Bone Disorders

5.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.7K
Disorders of Leukocytes01:27

Disorders of Leukocytes

2.1K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thyroid Function Parameters, Thyroid Status, and Vitamin B12 Deficiency in Hospitalized Adults: A Retrospective Cross-Sectional Study in Eastern India.

Cureus·2026
Same author

Prevention of endotracheal tube occlusion through process of standardisation of humidification during mechanical ventilation in a neonatal intensive care unit: A quality improvement initiative.

Tropical doctor·2026
Same author

Inflammatory biomarkers and sarcopenia in older adults.

Frontiers in aging·2026
Same author

Delirium in older hospitalized patients: a decade-later study highlighting medical and medication-related etiologies beyond muscarinic antagonism.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Temporal-Compositional Engineering of Manganese Ferrite Nanoparticles for Tunable Theranostic Performance.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

From Epigenetic Dysregulation to Therapeutic Reprogramming in Endometrial Cancer: A State-Response Framework for Treatment Resistance.

International journal of molecular sciences·2026

Related Experiment Video

Updated: Feb 26, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
11:25

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice

Published on: April 1, 2015

14.1K

Filariasis Presenting As Bone Marrow Suppression.

Anup Singh1, Sarita Kumari2

  • 1Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Journal of Ayub Medical College, Abbottabad : JAMC
|July 17, 2017
PubMed
Summary
This summary is machine-generated.

Lymphatic filariasis, caused by Wuchereria bancrofti, is typically diagnosed via microfilariae in blood or fluids. This case highlights an unusual finding of microfilariae in bone marrow associated with pancytopenia.

Keywords:
Bone MarrowMicrofilariaePancytopenia

More Related Videos

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
08:00

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model

Published on: October 14, 2016

21.3K
Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
06:33

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies

Published on: November 10, 2023

1.9K

Related Experiment Videos

Last Updated: Feb 26, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
11:25

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice

Published on: April 1, 2015

14.1K
A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
08:00

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model

Published on: October 14, 2016

21.3K
Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
06:33

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies

Published on: November 10, 2023

1.9K

Area of Science:

  • Tropical medicine
  • Hematology
  • Parasitology

Background:

  • Lymphatic filariasis is a significant public health concern in India, primarily caused by Wuchereria bancrofti.
  • Standard diagnostic methods involve detecting microfilariae in peripheral blood, body fluids, and fine needle aspirates.
  • Bone marrow involvement in lymphatic filariasis is rarely documented.

Observation:

  • A young male patient presented with pancytopenia, a condition characterized by a deficiency of all blood cell types.
  • Diagnostic investigations revealed the presence of microfilariae within the bone marrow aspirate.
  • This finding is atypical for lymphatic filariasis, which usually affects peripheral circulation.

Findings:

  • The bone marrow examination confirmed microfilariae in a patient with pancytopenia, suggesting an unusual manifestation of Wuchereria bancrofti infection.
  • This case challenges the conventional understanding of microfilariae localization in lymphatic filariasis.
  • The presence of microfilariae in bone marrow may be linked to the observed hematological abnormalities.

Implications:

  • This case broadens the diagnostic considerations for lymphatic filariasis, particularly in patients with unexplained cytopenias.
  • Further research is warranted to understand the pathogenesis of microfilariae in bone marrow and its impact on hematopoiesis.
  • Clinicians should consider bone marrow examination in endemic areas for patients presenting with similar hematological profiles.