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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Related Experiment Video

Updated: Feb 26, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
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Young Adults with Multiple Myeloma.

Hollie Devine, Daniel Verina

    Seminars in Oncology Nursing
    |July 18, 2017
    PubMed
    Summary

    Young adults (YAs) with multiple myeloma (MM) face unique survivorship challenges, including infertility and higher mortality risks. Oncology nurses must address these specific needs for better patient care.

    Area of Science:

    • Hematology
    • Oncology
    • Young Adult Health

    Background:

    • Multiple myeloma (MM) is a rare hematologic malignancy typically affecting older adults.
    • Young adults (YAs), aged 19-40, diagnosed with MM present distinct challenges compared to older populations.

    Purpose of the Study:

    • To identify the critical issues faced by young adults diagnosed with multiple myeloma.
    • To highlight the unique survivorship concerns in this rare demographic.

    Main Methods:

    • Literature review of peer-reviewed journal articles.
    • Inclusion of case reports and single-institution series.
    • Analysis of national guidelines for MM care.

    Main Results:

    • Young adults with MM experience longer survival but face increased survivorship issues.
    Keywords:
    fertilitymultiple myelomaoncologyyoung adults

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  • Key concerns include treatment adherence, infertility, reproductive health, secondary cancers, cardiotoxicity, and non-cancer mortality.
  • Developmental, psychosocial, and medical needs of YAs with MM are distinct.

    • Conclusions:

    • Young adults with MM require specialized care addressing unique survivorship challenges.
    • Oncology nurses play a crucial role in providing targeted education and advocating for patient-centered care.
    • Understanding the specific needs of YAs with MM is essential for improving outcomes and quality of life.