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Updated: Feb 26, 2026
Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
Published on: January 27, 2018
Cervical dystonia patients display subclinical gait changes
Marcello Esposito1, Raffaele Dubbioso1, Silvio Peluso1
1Department of Neurosciences, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Italy.
Introduction:
Gait disorders in cervical dystonia (CD) are reported in patients under DBS or in severe cases complicated with spinal deformities.
Objective:
to assess walking motor pattern in CD patients without DBS and not presenting scoliosis.
Methods:
Computerized gait analysis (CGA) was performed in CD patients, before and after botulinum toxin (BoNT) injections, and in healthy controls (HC). Spatiotemporal (ST) parameters were compared between CD and HC groups. Correlation analysis was conducted between ST parameters and clinical features of CD patients.
Results:
CD patients demonstrated a significant reduction of velocity, stride length, % of swing phase, and dynamic stability index while stride and swing time were increased. No significant effect of BoNT was detected. A significant inverse correlation was found between TWSTRS and stride length.
Conclusion:
CD patients may have a slow gait with subclinical evidence. Our data suggest this alteration might be an endophenotipic feature of CD.
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