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Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
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[Endometriosis and miscarriage: Systematic review].
H Minebois1, A De Souza1, C Mezan de Malartic1
1Maternité régionale universitaire, centre hospitalier universitaire de Nancy, rue Heydenreich, 54000 Nancy, France.
Gynecologie, Obstetrique, Fertilite & Senologie
|July 18, 2017
Summary
Endometriosis increases the risk of miscarriage in spontaneous pregnancies by nearly 80%. This meta-analysis evaluated the association between endometriosis and miscarriage, finding a significantly higher miscarriage rate in affected women.
Area of Science:
- Reproductive Medicine
- Gynecology
Background:
- Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus.
- Previous research suggests a potential link between endometriosis and adverse pregnancy outcomes.
Purpose of the Study:
- To evaluate the association between endometriosis and miscarriage in spontaneous pregnancies.
- To determine if endometriosis is a risk factor for miscarriage.
Main Methods:
- A systematic literature search was conducted in Cochrane Library and Medline from inception to December 2016.
- Included studies compared pregnant women with endometriosis to disease-free pregnant women.
- Meta-analysis followed PRISMA criteria, with miscarriage as the primary outcome.
Main Results:
- Four primary studies met inclusion criteria, comparing 225 abstracts.
- The miscarriage rate was significantly higher in the endometriosis group (OR 1.77 [CI 95% 1.13-2.78]).
Conclusions:
- Endometriosis appears to be a significant risk factor for miscarriage in spontaneous pregnancies.
- An almost 80% increased risk of miscarriage is associated with endometriosis.
- Further prospective studies are required to confirm these findings.
Keywords:
Avortement spontanéEndometriosisEndométrioseFausse couche spontanéeFetal lossGrossesse spontanéeMiscarriagePerte fœtaleSpontaneous abortionSpontaneous pregnancyMore Related Videos
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