Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual function in the newborn infant: is it cortically mediated?

L M Dubowitz, J Mushin, L De Vries

    Lancet (London, England)
    |May 17, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Glucocorticoid-prescribing trends in congenital adrenal hyperplasia, 2017 to 2023.

    Endocrine connections·2026
    Same author

    LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice.

    Peptides·2022
    Same author

    [COVID-19 during pregnancy and lactation: what do we already know?]

    Nederlands tijdschrift voor geneeskunde·2021
    Same author

    Bat-borne viruses in Africa: a critical review.

    Journal of zoology (London, England : 1987)·2020
    Same author

    Manipulation under anesthesia following total knee arthroplasty: a comprehensive review of literature.

    Musculoskeletal surgery·2018
    Same author

    A novel heterozygous IGF-1 receptor mutation associated with hypoglycemia.

    Endocrine connections·2017
    Same journal

    Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

    Lancet (London, England)·2026
    Same journal

    [<sup>177</sup>Lu]Lu-edotreotide versus everolimus for gastroenteropancreatic neuroendocrine tumours (COMPETE): a phase 3, multicentre, randomised, open-label, superiority trial.

    Lancet (London, England)·2026
    Same journal

    Research priorities for characterising Bundibugyo virus.

    Lancet (London, England)·2026
    Same journal

    Rethinking treatment sequence in advanced gastroenteropancreatic neuroendocrine tumours.

    Lancet (London, England)·2026
    Same journal

    Dual mobility total hip replacement in fractures: stability promotes patient confidence.

    Lancet (London, England)·2026
    Same journal

    Dual mobility versus standard cups in total hip replacement for displaced femoral neck fractures (Duality): an international, multicentre, randomised, controlled, superiority trial.

    Lancet (London, England)·2026
    See all related articles

    Premature infants show normal early visual function despite occipital cortex damage. This suggests subcortical pathways, not the cortex, initially mediate vision in neonates.

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Ophthalmology

    Background:

    • Assessing visual development in premature infants is crucial.
    • Understanding the neural basis of early vision is complex.
    • Occipital cortex development is critical for visual processing.

    Purpose of the Study:

    • To investigate the role of the occipital cortex in early visual function of premature infants.
    • To determine if subcortical pathways mediate visual responses in neonates with cortical abnormalities.

    Main Methods:

    • Observation of visual behavior in premature infants up to 48 weeks' postmenstrual age.
    • Electrophysiological assessment using visual evoked responses (VERs).
    • Correlation of neuroimaging findings (ultrasound) with behavioral and electrophysiological data.

    Related Experiment Videos

    Main Results:

    • Normal visual behavior observed in infants with severe occipital cortex destruction.
    • Symmetrical VERs recorded in neonates with asymmetrical occipital lesions.
    • Abnormal but present VERs in an infant lacking a visual cortex.
    • VER asymmetry developed later, around 2 months of age.

    Conclusions:

    • Early visual function in premature infants is largely independent of the occipital cortex.
    • Subcortical pathways appear to be the primary mediators of early visual behavior and electrophysiological responses.
    • These findings challenge traditional models of visual cortex dependency in early development.