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Extranasopharyngeal angiofibroma revisited.
1Department of Otorhinolaryngology, Head and Neck Surgery, Hospital of Maria Hilf, Moenchengladbach, Germany.
Summary
Extranasopharyngeal angiofibromas (ENAs) most commonly occur on the nasal septum, contrary to previous beliefs. These rare tumors require consideration in the differential diagnosis of upper airway masses, especially in adults.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Pathology
Background:
- Angiofibromas typically arise in the nasopharynx but can occur elsewhere in the head and neck.
- Extranasopharyngeal angiofibroma (ENA) is a rare condition with an incompletely understood incidence and clinical presentation.
Purpose of the Study:
- To evaluate the incidence and clinical features of extranasopharyngeal angiofibroma (ENA).
Main Methods:
- Systematic literature review of Medline and Google databases up to December 31, 2015.
- Analysis of 174 reported cases of ENA from 170 publications.
Main Results:
- The nasal septum is the most common site for ENA, contradicting prior understanding.
- The majority of patients presented with nasal obstruction, often with epistaxis; mean age was 28.7 years.
- Surgical resection was the primary treatment, with a low recurrence rate of 4/170.
Conclusions:
- ENA awareness is increasing, leading to more reported cases.
- ENAs should be considered in the differential diagnosis of nasal septal tumors, particularly in adults with rapid onset nasal obstruction.
- Transnasal resection is often sufficient, and recurrences are rare.
