Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

13.6K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
13.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Method for Fabricating Long Decellularized Scaffolds from Skeletal Muscle.

Tissue engineering. Part C, Methods·2026
Same author

Less frequent clinical and viral load assessments during COVID did not increase virological failure.

International journal of STD & AIDS·2026
Same author

Humanoid Robotic Loading Enhances Mechanotransduction in Tendon Tissue Engineering.

Cyborg and bionic systems (Washington, D.C.)·2026
Same author

Measuring Value in Orthopaedics: The U.S. and U.K. Perspectives.

The Journal of bone and joint surgery. American volume·2026
Same author

Switch to fixed-dose doravirine (100 mg) and islatravir (0·25 mg) once daily in virologically suppressed adults with HIV-1 on oral antiretroviral therapy: 48-week results of a phase 3, multicentre, randomised, open-label, non-inferiority trial.

Lancet (London, England)·2026
Same author

Translational Potential of an Electrospun Polycaprolactone Scaffold for Anterior Cruciate Ligament Reconstruction.

Advanced fiber materials·2026
Same journal

Effect of alloying and adding hydroxyapatite on the mechanical and corrosive properties of porous magnesium (Mg).

Journal of biomaterials applications·2026
Same journal

From leaf to cellulose scaffold: Decellularization and multi-scale characterization of <i>Neolamarckia cadamba</i> leaf for biomedical applications.

Journal of biomaterials applications·2026
Same journal

Gelatin-based cryogels seeded with exosomes enhance osteogenic activity and bone regeneration in a rabbit femoral defect model.

Journal of biomaterials applications·2026
Same journal

Carbon monoxide-releasing molecule-3 eradicates mature <i>Enterococcus faecalis</i> biofilms and inhibits recolonization.

Journal of biomaterials applications·2026
Same journal

Natural melanin nanoparticles modified with glycol chitosan for enhanced delivery of oxaliplatin.

Journal of biomaterials applications·2026
Same journal

Epidural thickness of the dura sealants HEMOPATCH® and TACHOSIL® after elective supratentorial craniotomy: A comparative retrospective monocentric cohort study.

Journal of biomaterials applications·2026
See all related articles

Related Experiment Video

Updated: Feb 26, 2026

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery
09:13

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery

Published on: October 6, 2022

4.2K

Synthetic sutures: Clinical evaluation and future developments.

Roxanna E Abhari1, Joana A Martins1, Hayley L Morris1

  • 1Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Old Road, Oxford, UK.

Journal of Biomaterials Applications
|July 18, 2017
PubMed
Summary
This summary is machine-generated.

Sutures have evolved little therapeutically over 4000 years. This review explores suture history, clinical evaluation, and regenerative medicine to develop bioactive sutures for improved surgical healing.

Keywords:
Suturesbioactiveclinical efficacyregenerative materialssynthetic absorbable

More Related Videos

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
06:36

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects

Published on: December 10, 2021

3.4K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

6.4K

Related Experiment Videos

Last Updated: Feb 26, 2026

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery
09:13

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery

Published on: October 6, 2022

4.2K
A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
06:36

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects

Published on: December 10, 2021

3.4K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

6.4K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Surgical Innovation

Background:

  • Sutures possess a 4000-year history of material and manufacturing advancements.
  • Current sutures primarily serve mechanical functions, with limited enhancement of therapeutic value.
  • Industry-driven development has led to incremental product modifications rather than significant therapeutic innovation.

Purpose of the Study:

  • To review the historical development and regulatory landscape of sutures.
  • To assess the extent of clinical evaluation for existing suture materials.
  • To explore the potential of tissue engineering and regenerative medicine in designing bioactive sutures.

Main Methods:

  • Historical analysis of suture manufacturing and companies.
  • Review of suture regulatory databases (e.g., Food and Drug Administration).
  • Systematic review of clinical literature on suture efficacy.
  • Application of regenerative medicine principles to suture material design.

Main Results:

  • Many current sutures lack comprehensive clinical evaluation despite long-term availability.
  • Suture development is largely driven by industry, focusing on incremental changes and regulatory compliance.
  • A shift towards academic interest in suture development is emerging, fueled by regenerative medicine.

Conclusions:

  • Bioactive sutures, leveraging tissue engineering, offer potential for enhanced therapeutic value and improved surgical outcomes.
  • The transition from inert to bioactive sutures requires addressing potential increases in regulatory burden, cost, and clinical evaluation.
  • Further research and development are needed to realize the full therapeutic potential of advanced suture materials.