Related Experiment Video

Updated: Aug 15, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

26.4K

Dedicated bifurcation stents or regular drug eluting stents in distal left main stenosis: A retrospective study

Adam Kern1, Robert J Gil, Krystian Bojko

  • 1Faculty of Medical Sciences University of Warmia and Mazury, Olsztyn, Poland. adamkern@mail.com.

Cardiology Journal
|July 18, 2017
PubMed

Insights

This study compared regular drug-eluting stents (rDES) and dedicated bifurcation stents for distal left main (LM) stenosis. Both stent types showed comparable rates of major adverse cardiovascular events (MACE) and target lesion revascularization (TLR) after 36 months.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Biology

Background:

  • Distal left main (LM) atherosclerosis commonly occurs at bifurcations or trifurcations.
  • Understanding treatment strategies for distal LM stenosis is crucial for patient outcomes.

Purpose of the Study:

  • To analyze treatment strategies for distal left main (LM) stenosis.
  • To evaluate clinical outcomes associated with different stent types in distal LM stenosis.

Main Methods:

  • A retrospective analysis of 102 patients with distal LM stenosis treated between June 2012 and June 2013.
  • Patients received either regular drug-eluting stents (rDES) or dedicated bifurcation stents (BiOSS LIM®).
  • Clinical outcomes, including major adverse cardiovascular events (MACE) and target lesion revascularization (TLR), were assessed at 12, 24, and 36 months.

Main Results:

  • 90 patients underwent percutaneous coronary intervention with no implantation failures.
  • After 36 months, the MACE rate was 19.0% (BiOSS: 18.8% vs. rDES: 19.2%) and the TLR rate was 10.7% (BiOSS: 12.5% vs. rDES: 9.6%).
  • Proximal optimization technique was associated with better TLR outcomes, while non-ST-elevation ACS, ST-elevation myocardial infarction, and side branch stenting were risk factors for poor outcomes.

Conclusions:

  • Both regular drug-eluting stents (rDES) and dedicated bifurcation BiOSS LIM® stents offer simple and effective treatment options for distal LM stenosis.
  • Comparable MACE and TLR rates were observed between the two stent types, suggesting similar long-term efficacy.
Abstract

Keywords:
BiOSSculotte techniquededicated bifurcation stentprovisional T-stenting

More Related Videos

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access05:04

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access

Published on: November 19, 2020

4.9K

Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...